Transpharmation Inc
Location
Centre Wellington, Ontario
Salary
CA$27 - CA$27 / HOUR
Perform in vivo study procedures and animal husbandry in the Rodent Department following OECD GLP and CCAC guidelines. Document experimental details accurately and assist in data summary reports and quality control.
Requires a Veterinary diploma or B.Sc. in a relevant field with at least 2 years of direct experience. Experience in a laboratory environment and familiarity with GLP and animal research regulations are essential.
Transpharmation is a dynamic preclinical contract research organization that specializes in high-quality, translational drug discovery services. The company provides a friendly and team-oriented work atmosphere as well as competitive wages and benefits.
The Research Technician II (“RT II”) will have a solid understanding of each individual’s roles and responsibilities within the company and within research studies. The RT II will have a clear understanding of and be able to perform a majority of the procedures at Transpharmation Canada within the Rodent Department. The RT II will demonstrate a clear understanding of the complexities of a research trial and be able to efficiently follow study protocols, with continued guidance from the Study Coordinator/Study Director/Scientific Director.
associated with the Rodent Wing General techniques: Operate centrifuges and perform advanced blood separation Proficient handling and restraint of rodents Health Observations (daily observations, endpoint monitoring) Drug administrations (SC, IM, IP, IV, PO, IN, intradermal, etc.) Survival blood collection (saphenous, tail snip, submandibular, catheter, etc.) Terminal blood collection, tissue/organ extraction and weighing Anaesthesia/Analgesia in support of surgery and animal welfare Euthanasia Seizure Testing: Perform and/or support seizure testing, including but not limited to: MES 6Hz Corneal Kindling Amygdala Kindling Pain Testing: Perform and/or support pain testing from start to end independently, including but not limited to: Von Frey Acetone drop Tail flick Formalin Behavioral testing: Prepare rooms and supplies for testing Possess ability to operate test apparatus for behavioral and cognitive testing (LMA, rotarod, grip strength, core body temperature, watermaze, running wheel, PPI, Moseq, as well as software application as it relates to the test,etc.) Various behavioural assessments and scoring EEG systems: DSI and TaiNi Operant testing (as applicable): Possess ability to independently run operant training and testing, as assigned and scheduled by Study Coordinator Rodent Abuse Liability (as applicable): General Behavioural Assessments Place Conditioning IV and Oral Self-administration Dependence and withdrawal assessment Basic formulation skills Surgery support, recovery, and endpoint monitoring Basic surgery skills IV catheter and osmotic pump implant care and maintenance Working with controlled substances Data Management: Ability to create basic graphs from experimental results Understand basic data analysis (means, standard error, median, interquartile) Any other duties as deemed necessary
This position requires coordination of resources (i.e. equipment, supplies) with other Research Technicians, Animal Care Technicians and Study Coordinators. It also requires the ability to learn new skills and procedures as well as teach skills efficiently and to a high level of integrity. COMMUNICATION
ENVIRONMENT There will be occasional periods of several hours per day exposed to noxious odours from diagnostic materials and/or samples. There will also be the occasional need to work with chemicals in a controlled environment.
RISK TO HEALTH There will be the occasional exposure to small quantities of toxic irritant or corrosive chemicals as well as exposure to freezers (-80C) while storing and retrieving materials.
standing, bending, twisting, lifting, carrying liquid containers, carrying boxes weighing up to 20 kg and daily periods of keyboarding.
PHYSICAL DEXTERITY Agility, accuracy and consistency will be required while handling precision instruments such as, pipettes, balances, pH meters, surgical instruments. Strong fine motor skills in fingers, hands, and arms.
EDUCATION Veterinary diploma or B.Sc. degree in a relevant field (e.g. Pharmacology, Pharmacokinetics, Veterinary Sciences, Biochemistry) and/or relevant equivalent with at least 2 years of direct experience. CALAS RLAT certification encouraged.
Experience Experience as a Research Technician I for at least 1 year or relevant experience Experience within a laboratory environment Experience handling confidential laboratory and scientific data Experience executing administrative strategies
Knowledge Knowledge of the basic principles of biology, immunology and chemistry Knowledge of the principles of safe handling of potentially pathogenic substances and contaminated materials Familiar with the following acts and regulations: ISO 17025 (2017), OECD Principles on GLP, CCAC guidelines and policies and the Animals for Research Act
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We are committed to fair, inclusive, and bias‑aware hiring practices and comply with Ontario legislation. If you require accommodation at any stage of the recruitment process, please let us know.
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